If your glycogen levels drop, you can lose half a kilogram -- over 1 pound. additionally, every gram of glycogen carries with it 3 grams of water, meaning that if you deplete your regular stores of glycogen, this can show up as a 2 kilogram loss on the scale.. Welcome to my science based guide to glycogen and weight loss. read this guide all the way through to find out what glycogen is, how much (water) weight it can help you lose, and what you need to do, to get rid of any glycogen-bound weight.. �